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HSP90 alpha Products

Antibodies
HSP90 alpha Antibody
HSP90 alpha Antibody
NB120-2928
Western Blot HSP90 alpha Antibody
Immunocytochemistry/ Immunofluorescence HSP90 alpha Antibody
Immunohistochemistry-Paraffin HSP90 alpha Antibody
Western Blot HSP90 alpha Antibody
Western Blot HSP90 alpha Antibody
Western Blot HSP90 alpha Antibody
Western Blot HSP90 alpha Antibody
Immunohistochemistry-Paraffin HSP90 alpha Antibody
Immunohistochemistry-Paraffin HSP90 alpha Antibody
Immunohistochemistry-Paraffin HSP90 alpha Antibody
Immunohistochemistry-Paraffin HSP90 alpha Antibody
Immunohistochemistry HSP90 alpha Antibody
Immunohistochemistry HSP90 alpha Antibody
Immunoprecipitation HSP90 alpha Antibody
Immunohistochemistry-Paraffin HSP90 alpha Antibody
LRP-1 autocrine loop" that promotes cell motility. (B) Western blot shows 231-wt and two clones of 231-Hsp90 alpha -knockout (231-alpha -KO) cells (panel a). (C) Anti-Hsp90 alpha antibody blotting of secreted Hsp90 alpha in serum-free conditioned medium (CM, 10X) from 231-wt, 231-alpha -KO (panel c) or 231-LRP-1-KD (panel d) cells. (D) Western blot analysis shows the total Hsp90 alpha level in 231-wt or 231-LRP-1-KD cells under normoxia or hypoxia. (E) Western blot analysis shows the relative levels of LRP-1 in indicated cell lines. (F) CM from 231-wt, but not 231-alpha -KO, cells stimulated B16 melanoma cell migration (panels k and l vs. panel i), with human recombinant (hr) Hsp90 alpha protein (panel j) as positive control. (G) Computer-assisted quantitation of the B16 cell migration shown in panel F as Migration Index (%) (“Methods"). CM from 231-alpha -KO cells completely lost pro-motility activity (panel l). Asterisks indicate significance of the induced migration by indicated stimuli (panels j, k) versus the serum-free control (panel i). (H) The indicated cells were simultaneously compared for their motility under serum-fee conditions. Neither total alpha -KO (panels o and s) nor extracellular blockade of secreted Hsp90 alpha function by mAb1G7-D7 (panels p, t) re-produced the degree of inhibition of cell motility by LRP-1-KD (panels n and u), in reference to 231-wt cells (panels m and q). (L) Computer-assisted quantitation of the cell migration data with indicated panels. Asterisks indicate the significance of indicated cell motility over that of the LRP-1-KD cells. All experiments were repeated multiple times to reach the final conclusion. Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/35835845), licensed under a CC-BY license. Not internally tested by Novus Biologicals." class="big_lightbox" target="_blank"> Western Blot HSP90 alpha Antibody
LRP-1 autocrine loop" that promotes cell motility. (B) Western blot shows 231-wt and two clones of 231-Hsp90 alpha -knockout (231-alpha -KO) cells (panel a). (C) Anti-Hsp90 alpha antibody blotting of secreted Hsp90 alpha in serum-free conditioned medium (CM, 10X) from 231-wt, 231-alpha -KO (panel c) or 231-LRP-1-KD (panel d) cells. (D) Western blot analysis shows the total Hsp90 alpha level in 231-wt or 231-LRP-1-KD cells under normoxia or hypoxia. (E) Western blot analysis shows the relative levels of LRP-1 in indicated cell lines. (F) CM from 231-wt, but not 231-alpha -KO, cells stimulated B16 melanoma cell migration (panels k and l vs. panel i), with human recombinant (hr) Hsp90 alpha protein (panel j) as positive control. (G) Computer-assisted quantitation of the B16 cell migration shown in panel F as Migration Index (%) (“Methods"). CM from 231-alpha -KO cells completely lost pro-motility activity (panel l). Asterisks indicate significance of the induced migration by indicated stimuli (panels j, k) versus the serum-free control (panel i). (H) The indicated cells were simultaneously compared for their motility under serum-fee conditions. Neither total alpha -KO (panels o and s) nor extracellular blockade of secreted Hsp90 alpha function by mAb1G7-D7 (panels p, t) re-produced the degree of inhibition of cell motility by LRP-1-KD (panels n and u), in reference to 231-wt cells (panels m and q). (L) Computer-assisted quantitation of the cell migration data with indicated panels. Asterisks indicate the significance of indicated cell motility over that of the LRP-1-KD cells. All experiments were repeated multiple times to reach the final conclusion. Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/35835845), licensed under a CC-BY license. Not internally tested by Novus Biologicals." class="big_lightbox" target="_blank"> Western Blot HSP90 alpha Antibody
Species: Hu, Mu, Rt, Pm, Rb, Sh
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
HSP90 alpha Antibody
HSP90 alpha Antibody
NBP2-16895
Immunohistochemistry-Paraffin HSP90 alpha Antibody
Western Blot HSP90 alpha Antibody
Immunohistochemistry-Paraffin HSP90 alpha Antibody
Immunohistochemistry-Paraffin HSP90 alpha Antibody
Immunohistochemistry-Paraffin HSP90 alpha Antibody
Immunohistochemistry-Paraffin HSP90 alpha Antibody
Western Blot HSP90 alpha Antibody
Immunocytochemistry/ Immunofluorescence HSP90 alpha Antibody
Western Blot HSP90 alpha Antibody
Species: Hu, Mu, Rt, Dr, In, Pm, Po, Bv, Ch, Pm, RM
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
HSP90 alpha Antibody - BSA Fr ...
HSP90 alpha Antibody - BSA Free
NBP1-77682
Immunocytochemistry/ Immunofluorescence HSP90 alpha Antibody - BSA Free
Immunohistochemistry HSP90 alpha Antibody - BSA Free
Species: Hu, Mu
Applications: Flow, ICC/IF, IHC
Host: Rabbit Polyclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 NBP1-77682AF350
Alexa Fluor 405 NBP1-77682AF405
Alexa Fluor 488 NBP1-77682AF488
Alexa Fluor 532 NBP1-77682AF532
Alexa Fluor 594 NBP1-77682AF594
Alexa Fluor 647 NBP1-77682AF647
Alexa Fluor 700 NBP1-77682AF700
Alexa Fluor 750 NBP1-77682AF750
Allophycocyanin NBP1-77682APC
Biotin NBP1-77682B
CoraFluor 1 NBP1-77682CL1
DyLight 350 NBP1-77682UV
DyLight 405 NBP1-77682V
DyLight 488 NBP1-77682G
DyLight 550 NBP1-77682R
DyLight 594 NBP1-77682DL594
DyLight 650 NBP1-77682C
DyLight 680 NBP1-77682FR
DyLight 755 NBP1-77682IR
FITC NBP1-77682F
HRP NBP1-77682H
Janelia Fluor 525 NBP1-77682JF525
Janelia Fluor 549 NBP1-77682JF549
Janelia Fluor 646 NBP1-77682JF646
Janelia Fluor 669 NBP1-77682JF669
PE NBP1-77682PE
PerCP NBP1-77682PCP
mFluor Violet 450 SE NBP1-77682MFV450
mFluor Violet 500 SE NBP1-77682MFV500
mFluor Violet 610 SE NBP1-77682MFV610
Formulation Catalog # Availability Price  
BSA Free NBP1-77682SS
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We have 32 HSP90 alpha Antibodies
ELISA Kits
Human HSP90 alpha - Ready-To ...
Human HSP90 alpha - Ready-To-Use ...
NBP3-31874
ELISA Human HSP90 alpha - Ready-To-Use ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
Human HSP90 alpha ELISA Kit ( ...
Human HSP90 alpha ELISA Kit (Color...
NBP3-31873
ELISA Human HSP90 alpha ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
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We have 2 HSP90 alpha ELISA Kits
Lysates
HSP90 alpha Overexpression Ly ...
HSP90 alpha Overexpression Lysate
NBL1-11743
Western Blot HSP90 alpha Overexpression Lysate
Species: Hu
Applications: WB
HSP90 alpha Overexpression Ly ...
HSP90 alpha Overexpression Lysate
NBL1-11744
Western Blot HSP90 alpha Overexpression Lysate
Species: Hu
Applications: WB
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We have 2 HSP90 alpha Lysates
Proteins
Recombinant Human HSP90 alpha ...
Recombinant Human HSP90 alpha Prot...
AP-160
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Carrier Free AP-160-050
HSP90 alpha Antibody Blocking ...
HSP90 alpha Antibody Blocking Peptide
NBP1-77682PEP
Applications: AC
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We have 2 HSP90 alpha Proteins

Description

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding,protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and playimportant roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress.There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutiveform. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM606219) (Chen et al., 2005 (PubMed 16269234)).(supplied by OMIM)

Bioinformatics

Entrez
1168
Human
15519
Mouse
299331
Rat
3320
Human
Uniprot
NM_001017963
Human
NM_005348
Human
NP_005339
Human
P07900
Human
P07901
Mouse
P82995
Rat
Q2M3G0
Human
Product By Gene ID 3320
Alternate Names
  • FLJ31884
  • Heat shock 86 kDa
  • heat shock 90kD protein 1, alpha
  • heat shock 90kD protein 1, alpha-like 4
  • heat shock 90kD protein, alpha-like 4
  • heat shock 90kDa protein 1, alpha
  • heat shock protein 90kDa alpha (cytosolic), class A member 1
  • heat shock protein HSP 90-alpha
  • Hsp89
  • Hsp90
  • HSP90AHSP86
  • HSP90N
  • HSPC1HSP 86
  • HSPCAHSP89A
  • HSPCAL1
  • HSPCAL4
  • HSPN
  • LAP2
  • Renal carcinoma antigen NY-REN-38

Research Areas for HSP90 alpha

Find related products by research area and learn more about each of the different research areas below.

Cancer
Hypoxia
Membrane Trafficking and Chaperones

Related HSP90 alpha Blog Posts

Check out the latest blog posts on HSP90 alpha.
Hsp90A - helping to fold a wide variety of signal transduction proteins
Heat-shock protein 90 (Hsp90) is a conserved ATP-dependent chaperone with diverse cellular functions. Hsp90 is ubiquitously expressed but is further induced upon cellular stress such as heat-shock or nutrient deprivation. Hsp90 is essential for the...    Read more.
Read more HSP90 alpha related blogs.