HSBP1 Products

Antibodies
HSBP1 Antibody (2C3)
HSBP1 Antibody (2C3)
H00003281-M02
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Proteins
HSBP1 Recombinant Protein
HSBP1 Recombinant Protein
NBC1-18355
Species: Hu
Applications: PAGE
HSBP1 Recombinant Protein
HSBP1 Recombinant Protein
NBP1-99581
Species: Hu
RNAi
HSBP1 RNAi
HSBP1 RNAi
H00003281-R01
Species: Hu

Description

The heat-shock response is elicited by exposure of cells to thermal and chemical stress and through the activation ofHSFs (heat shock factors) results in the elevated expression of heat-shock induced genes. Heat shock factor bindingprotein 1 (HSBP1), is a 76-amino-acid protein that binds to heat shock factor 1(HSF1), which is a transcription factorinvolved in the HS response. During HS response, HSF1 undergoes conformational transition from an inertnon-DNA-binding monomer to active functional trimers. HSBP1 is nuclear-localized and interacts with the activetrimeric state of HSF1 to negatively regulate HSF1 DNA-binding activity. Overexpression of HSBP1 in mammalian cellsrepresses the transactivation activity of HSF1. When overexpressed in C.elegans HSBP1 has severe effects on survivalof the animals after thermal and chemical stress consistent with a role of HSBP1 as a negative regulator of heat shockresponse. (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 3281
Alternate Names
  • DKFZp686D1664
  • HSF1BP
  • NPC-A-13
  • heat shock factor-binding protein 1
  • Nasopharyngeal carcinoma-associated antigen 13
  • DKFZp686O24200
  • heat shock factor binding protein 1

Bioinformatics Tool for HSBP1

Discover related pathways, diseases and genes to HSBP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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