HOXD11 Products

Description

HOXD11 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis.

Bioinformatics

Entrez	3237 Human
Uniprot	NP_067015 Human
Product By Gene ID	3237
Alternate Names	homeo box D11 homeobox D11 Homeobox protein Hox-4F homeobox protein Hox-D11 HOX4 Hox-4.6, mouse, homolog of HOX4Fhomeo box 4F

Diseases related to HOXD11

Discover more about diseases related to HOXD11.

Limb Deformities, Congenital
Malignant Neoplasms
Polydactyly
Neoplasms
Syndactyly
Hypoplasia
Malignant Neoplasm Of Breast
Carcinoma
Dysplasia
Myeloid Leukemia
Ovarian Neoplasm
Rheumatoid Arthritis
Congenital Absence
Hematologic Neoplasms
Congenital Abnormality
Arthritis
Growth Arrest
Endometrial Polyp
Leukemia, Myelocytic, Acute

Pathways for HOXD11

View related products by pathway and learn more about each of the pathways below.

Limb Development
Methylation
Pathogenesis
Kidney Development
Reverse Transcription
Cell Proliferation
Ureteric Bud Formation
Transposition
Limb Morphogenesis
Cell Differentiation
Gastrulation
Regeneration
Cell Death
Transport
Programmed Cell Death
Gene Silencing
Regulation Of Gene Expression
Sex Determination
Ossification
Chondrocyte Differentiation

PTMs for HOXD11

Learn more about PTMs related to HOXD11.

Methylation
Demethylation

Bioinformatics Tool for HOXD11

Discover related pathways, diseases and genes to HOXD11. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.