Species: Hu, Mu, Rt, Po, Bv, Ch
Applications: WB, ICC/IF, IHC, IP, PAGE
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA, IHC, MA
Host: Mouse Monoclonal
Description
HNF1 is a transcription factor required for the expression of several liver-specific genes. The protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Bioinformatics
| Product By Gene ID |
6927 |
| Alternate Names |
- HNF1 homeobox A
- IDDM20
- LFB1transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albuminproximal factor
- MODY3
- TCF1hepatic
- Transcription factor 1
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