Hu, Mu, Rt, Po, Bv, ChApplications:
WB, ICC/IF, IHC, IHC-P, IP, PAGEHost:
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Applications: ELISA, IHC, IHC-P, PA
Host: Mouse Monoclonal
TCF 1 (T cell factor 1) is a member of the TCF/LEF (lymphoid enhancer factor) family of transcription factors. Members of this family along with 226; catenin, are involved in mediating Wnt signaling by transactivating downstream genes. TCF 1 is closely related to LEF-1, both of which are transcription factors expressed in mice during T cell differentiation. They regulate the T cell receptor 225; enhancer in transfections assays. TCF 1 becomes transcriptionally active through interaction with 226; catenin. Also, numerous splice variants of TCF 1 have been identified. Overexpression of TCF-1-specific splice forms appears to correlate with the metastatic behavior of colorectal cancer cells and with overproduction of lymphoid tyrosine protein kinase p56(lck).
|Product By Gene ID
- Transcription factor 1
- LFB1transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albuminproximal factor
- HNF1 homeobox A
Bioinformatics Tool for HNF1
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