HNF1 Products

Antibodies
HNF1 Antibody
HNF1 Antibody
Species: Hu, Mu, Rt, Bovine, Chicken, Porcine
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
HNF1 Antibody
HNF1 Antibody
NBP2-38243
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
HNF1 Antibody (4110)
HNF1 Antibody (4110)
NBP2-43652
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Mouse Monoclonal
Lysates
HNF1 Overexpression Lysate (N ...
HNF1 Overexpression Lysate (Native)
NBL1-11630
Applications: WB
Proteins
HNF1 Recombinant Protein Anti ...
HNF1 Recombinant Protein Antigen
NBP2-38243PEP
Species: Hu
Applications: AC
RNAi
HNF1 RNAi
HNF1 RNAi
H00006927-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

TCF 1 (T cell factor 1) is a member of the TCF/LEF (lymphoid enhancer factor) family of transcription factors. Members of this family along with 226; catenin, are involved in mediating Wnt signaling by transactivating downstream genes. TCF 1 is closely related to LEF-1, both of which are transcription factors expressed in mice during T cell differentiation. They regulate the T cell receptor 225; enhancer in transfections assays. TCF 1 becomes transcriptionally active through interaction with 226; catenin. Also, numerous splice variants of TCF 1 have been identified. Overexpression of TCF-1-specific splice forms appears to correlate with the metastatic behavior of colorectal cancer cells and with overproduction of lymphoid tyrosine protein kinase p56(lck).

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Product By Gene ID 6927
Alternate Names
  • Transcription factor 1
  • IDDM20
  • TCF1hepatic
  • LFB1transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albuminproximal factor
  • MODY3
  • HNF1 homeobox A

Research Areas for HNF1

Find related products by research area and learn more about each of the different research areas below.

Transcription Factors and Regulators

Bioinformatics Tool for HNF1

Discover related pathways, diseases and genes to HNF1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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