HMGN2 Products

Antibodies
HMGN2 Antibody
HMGN2 Antibody
NBP1-98427
Species: Mu
Applications: WB
Host: Rabbit Polyclonal
Proteins
HMGN2 Recombinant Protein
HMGN2 Recombinant Protein
H00003151-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
HMGN2 RNAi
HMGN2 RNAi
H00003151-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

HMG17 (high mobility group transcription factor 17) is an 18 kD high mobility group chromosomal protein. This nuclear protein is common to all eukaryotes and is developmentally regulated. HMG17 binds DNA in a non-sequence specific manner and interacts with nucleosomes to modulate chromatin structure. HMG17 regulates the gene expression of p53, Hox transcription factors, and steroid hormone receptors (increases DNA binding affinity). Phosphorylation of HMG17 may interfere with nuclear localization and favor release from nuclei. HMG17 is upregulated by wild-type p53 and increases during embryogenesis and is downregulated during differentiation and development. This protein is modified by phosphorylation and acetylation. HMG17 interacts with nucleosomes and probably forms multi-unit complexes with unrelated proteins. The Poly6081 antibody recognizes human and mouse HMG17 and has been shown to be useful for Western blotting.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 3151
Alternate Names
  • MGC5629
  • nonhistone chromosomal protein HMG-17
  • High mobility group nucleosome-binding domain-containing protein 2
  • non-histone chromosomal protein HMG-17
  • high-mobility group (nonhistone chromosomal) protein 17
  • HMG17high mobility group protein N2
  • MGC88718
  • high-mobility group nucleosomal binding domain 2

PTMs for HMGN2

Learn more about PTMs related to HMGN2.

Phosphorylation
Acetylation
Cleavage
Methylation

Bioinformatics Tool for HMGN2

Discover related pathways, diseases and genes to HMGN2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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