HMGN1/HMG14 Products

Antibodies
HMGN1/HMG14 Antibody
HMGN1/HMG14 Antibody
NBP2-14842
Species: Hu, Po, Bv, Ca, Pm, Rb
Applications: WB
Host: Rabbit Polyclonal
HMGN1/HMG14 Antibody
HMGN1/HMG14 Antibody
NBP2-47433
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
HMGN1/HMG14 [p Ser20, p Ser24 ...
HMGN1/HMG14 [p Ser20, p Ser24] Ant...
NBP1-78102
Species: Hu, Sh
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
HMGN1/HMG14 Overexpression Ly ...
HMGN1/HMG14 Overexpression Lysate ...
NBL1-11619
Applications: WB
Proteins
HMGN1/HMG14 Recombinant Prote ...
HMGN1/HMG14 Recombinant Protein An...
NBP2-47433PEP
Species: Hu
Applications: AC
HMGN1/HMG14 Recombinant Prote ...
HMGN1/HMG14 Recombinant Protein
NBP1-41146
Species: Hu
Applications: PAGE
RNAi
HMGN1/HMG14 RNAi
HMGN1/HMG14 RNAi
H00003150-R01
Species: Hu

Description

HMGNs are proteins that bind chromatin effectively reducing the compaction of the chromatin fiber and enhancing access to DNA regulatory sequences. Members of this family have a conserved chromatin binding domain which is phosphorylated during mitosis. The sequence immunized is conserved in several species. As such, this reagent is designed as a universal reagent for the detection of all phosphorylated HMGN proteins. The High Mobility Group (HMG) proteins were originally isolated from mammalian cells and were named according to their electrophoretic mobility in polyacrylamide gels. HMGs were arbitrarily classed as a specific type of nonhistone proteins based on the observation that they are ubiquitous to mammalian cells, that they share certain physical properties, and that they are associated with isolated chromatin. HMG proteins and are now subdivided into 3 families: the HMGB (formerly HMG-1/-2) family, the HMGN (formerly HMG-14/-17) family, and the HMGA (formerly HMG-I/Y/C) family. Each HMG family has a characteristic functional sequence motif. The functional motif of the HMGB family is called the "HMG-box;" that of the HMGN family, the "nucleosomal binding domain;" and that of the HMGA family, the "AT-hook." The functional motifs characteristic of these canonical HMGs are widespread among nuclear proteins in a variety of organisms. Proteins containing any of these functional motifs embedded in their sequence are known as "HMG motif proteins."

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 3150
Alternate Names
  • high-mobility group (nonhistone chromosomal) protein 14
  • nonhistone chromosomal protein HMG-14
  • MGC117425
  • non-histone chromosomal protein HMG-14
  • MGC104230
  • high-mobility group nucleosome binding 1
  • FLJ31471
  • HMG14FLJ27265
  • High mobility group nucleosome-binding domain-containing protein 1
  • high-mobility group nucleosome binding domain 1

PTMs for HMGN1/HMG14

Learn more about PTMs related to HMGN1/HMG14.

Phosphorylation
Acetylation
Deamination
Methylation
Dephosphorylation

Bioinformatics Tool for HMGN1/HMG14

Discover related pathways, diseases and genes to HMGN1/HMG14. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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