HLA DQA1 Products

Antibodies
HLA DQA1 Antibody
HLA DQA1 Antibody
NBP1-84550
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
HLA DQA1 Antibody (1A3)
HLA DQA1 Antibody (1A3)
H00003117-M01
Species: Hu
Applications: WB, ELISA, PLA
Host: Mouse Monoclonal
Lysates
HLA DQA1 Overexpression Lysat ...
HLA DQA1 Overexpression Lysate (Na...
NBL1-11584
Applications: WB
HLA DQA1 Overexpression Lysat ...
HLA DQA1 Overexpression Lysate (De...
H00003117-T02
Species: Hu
Applications: WB
Proteins
Recombinant Human HLA DQA1 Pr ...
Recombinant Human HLA DQA1 Protein
H00003117-Q01
Species: Hu
Applications: WB, ELISA, PA
HLA DQA1 Recombinant Protein ...
HLA DQA1 Recombinant Protein Antigen
NBP1-84550PEP
Species: Hu
Applications: AC
RNAi
HLA DQA1 RNAi
HLA DQA1 RNAi
H00003117-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 3117
Alternate Names
  • HLA-DQA
  • MHC HLA-DQ alpha
  • GSE
  • MHC class II surface glycoprotein
  • FLJ27328
  • MHC class II HLA-DQ-alpha-1
  • FLJ27088
  • MHC class II HLA-D alpha glycoprotein
  • DQ-A1
  • MHC class II antigen
  • CD
  • leukocyte antigen alpha chain
  • MHC class II DQA1
  • leucocyte antigen DQA1
  • DC-1 alpha chain
  • HLA class II histocompatibility antigen, DQ(W3) alpha chain
  • HLA-DCA
  • CELIAC1DQ alpha 1 chain
  • MGC149527
  • major histocompatibility complex, class II, DQ alpha 1

Research Areas for HLA DQA1

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Asthma
Immunology

PTMs for HLA DQA1

Learn more about PTMs related to HLA DQA1.

Biotinylation
Cleavage
Acetylation

Bioinformatics Tool for HLA DQA1

Discover related pathways, diseases and genes to HLA DQA1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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