HLA C Products

Antibodies
Antibody Pairs
HLA C Antibody Pair
HLA C Antibody Pair
H00003107-PW1
Species: Hu
Applications: WB, IP
Lysates
HLA C Overexpression Lysate ( ...
HLA C Overexpression Lysate (Denat...
H00003107-T01
Species: Hu
Applications: WB
HLA C Overexpression Lysate ( ...
HLA C Overexpression Lysate (Native)
NBL1-11594
Applications: WB
Proteins
HLA C Recombinant Protein
HLA C Recombinant Protein
NBP2-23210
Species: Hu
Applications: PAGE
RNAi
HLA C RNAi
HLA C RNAi
H00003107-R02
Species: Hu

Description

HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 3107
Alternate Names
  • MHC class I antigen heavy chain HLA-C
  • MHC class I antigen Cw*8
  • major histocompatibility antigen HLA-C
  • MHC class I antigen Cw*7
  • leukocyte antigen-C alpha chain
  • MHC class I antigen Cw*6
  • leucocyte antigen Cw
  • MHC class I antigen Cw*5
  • leucocyte antigen C
  • MHC class I antigen Cw*4
  • human leukocyte antigen-C alpha chain
  • MHC class I antigen Cw*3
  • HLA class I histocompatibility antigen, Cw-1 alpha chain
  • MHC class I antigen Cw*2
  • C alpha chain
  • MHC class I antigen Cw*17
  • HLC-C
  • MHC class I antigen Cw*16
  • HLA-Cw
  • MHC class I antigen Cw*15
  • FLJ27082
  • MHC class I antigen Cw*14
  • PSORS1
  • MHC class I antigen Cw*12
  • HLA-JY3
  • MHC class I antigen Cw*1
  • D6S204
  • HLAC
  • major histocompatibility complex, class I, C

Research Areas for HLA C

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Immunology

Bioinformatics Tool for HLA C

Discover related pathways, diseases and genes to HLA C. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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