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HLA-ABCE Products


Description

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Classical human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules, the non-classical by e.g. HLA-E, HLA-G.

Bioinformatics

Alternate Names
  • HLA-ABC
  • HLA-E
  • major histocompatibility complex, class I, A
  • major histocompatibility complex, class I, B
  • major histocompatibility complex, class I, C
  • major histocompatibility complex, class I, E
  • MHC class I