HLA A Products

Antibodies
HLA A Antibody
HLA A Antibody
H00003105-B01P
Species: Hu
Applications: WB, ELISA, Flow
Host: Mouse Polyclonal
HLA A Antibody
HLA A Antibody
H00003105-D01P
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
HLA A Antibody (108-2C5)
HLA A Antibody (108-2C5)
NBP2-45320
Species: Hu
Applications: Flow, IF
Host: Mouse Monoclonal
Antibody Pairs
HLA A Antibody Pair
HLA A Antibody Pair
H00003105-AP21
Species: Hu
Applications: S-ELISA
HLA A Antibody Pair
HLA A Antibody Pair
H00003105-PW1
Species: Hu
Applications: WB, IP
Lysates
HLA A Overexpression Lysate ( ...
HLA A Overexpression Lysate (Denat...
H00003105-T01
Species: Hu
Applications: WB
HLA A Overexpression Lysate ( ...
HLA A Overexpression Lysate (Native)
NBL1-11581
Applications: WB
Proteins
HLA A Recombinant Protein
HLA A Recombinant Protein
H00003105-P01
Species: Hu
Applications: PAGE
RNAi
HLA A RNAi
HLA A RNAi
H00003105-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 3105
Alternate Names
  • MHC class I antigen A*80
  • A-10 alpha chain
  • MHC class I antigen A*11
  • FLJ26655
  • MHC class I antigen A*1
  • HLA class I histocompatibility antigen, A-1 alpha chain
  • HLA class I histocompatibility antigen, A-9 alpha chain
  • HLAA
  • HLA class I histocompatibility antigen, A-28 alpha chain
  • major histocompatibility complex, class I, A

Research Areas for HLA A

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Cell Biology
Immunology

Bioinformatics Tool for HLA A

Discover related pathways, diseases and genes to HLA A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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