Species: Hu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Histones are nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber as they play a critical role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Histone H1.1 is a 215 amino acid long, 21 kDA protein encoded by the HIST1H1A gene. H1 proteins are essential in forming chromatin fiber and for the condensation of nucleosome chains into higher-order structured fibers. The HIST1H1A gene is active in apoptosis, PKA signaling, histone modification, and granzyme-A pathways. It interacts with genes CDK2, CDK7, CTCFL, DOT1L, and ADPRH. The HIST1H1A gene has been researched regarding measles, breast cancer, prostatitis, carcinoma, paratyphoid fever, and neuronitis.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human |
Product By Gene ID |
3024 |
Alternate Names |
- H1 histone family, member 1
- H1.1
- H1A
- H1F1HIST1
- histone 1, H1a
- histone cluster 1, H1a
- histone H1.1
- MGC126642
- MGC138345
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