Species: Hu, Mu, Rt, Ba
Applications: WB, IHC, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Huntingtin Interacting Protein (HIP1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin's disease. Huntingtin's is a neurodegenerate disease caused by the expansion of a polymorphic glutamine tract in Huntingtin.
In addition to playing a role in Huntingtin disease, HIP1 is likely to be involved in the recruitment of clathrin coats to lipid membranes, and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.
Bioinformatics
| Entrez |
Rat
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
9026 |
| Alternate Names |
- FLJ14000
- HIP-12
- HIP12HIP1-related protein
- HIP3
- huntingtin interacting protein 1 related
- huntingtin interacting protein 12
- Huntingtin-interacting protein 12
- huntingtin-interacting protein 1-related protein
- ILWEQ
- KIAA0655FLJ27022
- MGC47513
|
