HIF-3 alpha Products

Antibodies
HIF-3 alpha Antibody - BSA Fr ...
HIF-3 alpha Antibody - BSA Free
NBP1-89977
Species: Hu
Applications: IHC, ChIP
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
HIF-3 alpha Antibody - Azide ...
HIF-3 alpha Antibody - Azide and B...
H00064344-B02P
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
Lysates
HIF-3 alpha Overexpression Ly ...
HIF-3 alpha Overexpression Lysate
NBP2-05309
Species: Hu
Applications: WB
Proteins
Recombinant Human HIF-3 alpha ...
Recombinant Human HIF-3 alpha GST ...
H00064344-P01
Species: Hu
Applications: WB, ELISA, MA, AP
HIF-3 alpha Recombinant Prote ...
HIF-3 alpha Recombinant Protein An...
NBP1-89977PEP
Species: Hu
Applications: AC

Description

The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 64344
Alternate Names
  • Basic-helix-loop-helix-PAS protein MOP7
  • BHLHe17
  • bHLHe17HIF-3A2
  • Class E basic helix-loop-helix protein 17
  • HIF-3 alpha
  • HIF3A
  • HIF-3A4
  • HIF-3-alpha
  • HIF3-alpha
  • hypoxia inducible factor 3, alpha subunit
  • hypoxia-inducible factor 3-alpha
  • hypoxia-inducible factor-3 alpha 4
  • Inhibitory PAS domain protein
  • IPAS
  • IPASHIF3-alpha-1
  • Member of PAS protein 7
  • MOP7
  • MOP7PAS domain-containing protein 7
  • PASD7
  • PASD7HIF-3A

Research Areas for HIF-3 alpha

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Hypoxia

Related HIF-3 alpha Blog Posts

Check out the latest blog posts on HIF-3 alpha.
HIF-2 alpha: HIF1A's Homologue with Similar and Divergent Functions
HIF-2 alpha is a member of the heterodimeric hypoxia-inducible factors/HIFs family (HIF-1, HIF-2, and HIF-3) which contains a common beta subunit but differ in their alpha subunits. Also called as EPAS1 or Mop2, HIF-2 alpha regulates cellular adapt...    Read more.
HIF-3 alpha: a versatile target with hypoxia dependent and independent functions
By: Subhash GangarHIF-3 alpha (hypoxia-inducible factor 3-alpha/ HIF3A) represents an isoform of HIF-alpha subunits which heterodimerize with stable beta subunit (HIF-beta) for the regulation of HIF target genes through binding to hypoxia respon...    Read more.
HIF Prolyl Hydroxylase 2: an important Oxygen Sensor Protein
Prolyl hydroxylase domain (PHD) proteins, including PHD1, PHD2, and PHD3, mediate oxygen-dependent degradation of hypoxia-inducible factor (HIF) alpha subunits. Suppression of PHD enzymes leads to stabilization of HIFs and offers a potential treatment...    Read more.
HIF Antibodies: Beyond HIF-1 alpha
The hypoxia inducible factors are a family of heterodimeric transcription factors which are activated in response to lowered oxygen levels, or hypoxia. Although it may seem that HIF-1 alpha receives all the attention, other HIF antibodies, such as the...    Read more.
A Role for HIF-1 alpha Antibody in Renal Research
The Hypoxia Inducible Factors (HIFs) are a family of mammalian transcription factors which are expressed in response to low cellular oxygen concentrations (hypoxia). Three human hypoxia inducible factors have been identified, HIF-1, HIF-2 and HIF-3, e...    Read more.
Read more HIF-3 alpha related blogs.