HIF-3 alpha Products

Antibodies
HIF-3 alpha Antibody
HIF-3 alpha Antibody
NB100-2529
Species: Hu, Mu
Applications: WB, ICC/IF, IP
Host: Rabbit Polyclonal
Conjugate Catalog # Availability Size Price
HIF-3 alpha Antibody
HIF-3 alpha Antibody
NBP1-03155
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
HIF-3 alpha Overexpression Ly ...
HIF-3 alpha Overexpression Lysate ...
H00064344-T01
Species: Hu
Applications: WB
HIF-3 alpha Overexpression Ly ...
HIF-3 alpha Overexpression Lysate ...
H00064344-T02
Species: Hu
Applications: WB
HIF-3 alpha Overexpression Ly ...
HIF-3 alpha Overexpression Lysate ...
NBP2-05309
Applications: WB
Proteins
Recombinant Human HIF-3 alpha ...
Recombinant Human HIF-3 alpha Protein
H00064344-P01
Species: Hu
Applications: WB, ELISA, PA
HIF-3 alpha Recombinant Prote ...
HIF-3 alpha Recombinant Protein An...
NBP1-89977PEP
Species: Hu
Applications: AC
RNAi
HIF-3 alpha RNAi
HIF-3 alpha RNAi
H00064344-R01
Species: Hu
Applications: RNAi, RNAi SP
HIF-3 alpha RNAi
HIF-3 alpha RNAi
H00064344-R02
Species: Hu
Applications: RNAi, RNAi SP
HIF-3 alpha RNAi
HIF-3 alpha RNAi
H00064344-R03
Species: Hu
Applications: RNAi, RNAi SP

Description

Hypoxia-inducible factor (HIF) is one of the most important factors in the cellular response to hypoxia, by transcriptionally activating genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a heterodimer consisting of one of three subunits, HIF1 alpha, HIF2 alpha, or HIF3 alpha. HIF target genes play critical roles in metabolism, angiogenesis, cell proliferation and cell survival. HIF3 alpha protein is one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha 3 subunit lacks the transactivation domain found in factors containing either the alpha 1 or alpha 2 subunits. HIF3 alpha may be a marker for tumor growth and angiogenesis.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 64344
Alternate Names
  • BHLHE17
  • HIF-3-alpha
  • hypoxia-inducible factor-3 alpha 4
  • Member of PAS protein 7
  • hypoxia-inducible factor 3-alpha
  • Inhibitory PAS domain protein
  • Class E basic helix-loop-helix protein 17
  • HIF-3A4
  • Basic-helix-loop-helix-PAS protein MOP7
  • bHLHe17HIF-3A2
  • PASD7HIF-3A
  • MOP7PAS domain-containing protein 7
  • IPASHIF3-alpha-1
  • HIF3-alpha
  • hypoxia inducible factor 3, alpha subunit

Research Areas for HIF-3 alpha

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Chromatin Research
HIF Target Genes
Hypoxia
Transcription Factors and Regulators

PTMs for HIF-3 alpha

Learn more about PTMs related to HIF-3 alpha.

Hydroxylation
Oxidation

Bioinformatics Tool for HIF-3 alpha

Discover related pathways, diseases and genes to HIF-3 alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related HIF-3 alpha Blog Posts

Check out the latest blog posts on HIF-3 alpha.
HIF-2 alpha: HIF1A's Homologue with Similar and Divergent Functions
HIF-2 alpha is a member of the heterodimeric hypoxia-inducible factors/HIFs family (HIF-1, HIF-2, and HIF-3) which contains a common beta subunit but differ in their alpha subunits. Also called as EPAS1 or Mop2, HIF-2 alpha regulates cellular adapt...    Read more.
HIF-3 alpha: a versatile target with hypoxia dependent and independent functions
By: Subhash GangarHIF-3 alpha (hypoxia-inducible factor 3-alpha/ HIF3A) represents an isoform of HIF-alpha subunits which heterodimerize with stable beta subunit (HIF-beta) for the regulation of HIF target genes through binding to hypoxia respon...    Read more.
HIF Prolyl Hydroxylase 2: an important Oxygen Sensor Protein
Prolyl hydroxylase domain (PHD) proteins, including PHD1, PHD2, and PHD3, mediate oxygen-dependent degradation of hypoxia-inducible factor (HIF) alpha subunits. Suppression of PHD enzymes leads to stabilization of HIFs and offers a potential treatment...    Read more.
HIF Antibodies: Beyond HIF-1 alpha
The hypoxia inducible factors are a family of heterodimeric transcription factors which are activated in response to lowered oxygen levels, or hypoxia. Although it may seem that HIF-1 alpha receives all the attention, other HIF antibodies, such as the...    Read more.
A Role for HIF-1 alpha Antibody in Renal Research
The Hypoxia Inducible Factors (HIFs) are a family of mammalian transcription factors which are expressed in response to low cellular oxygen concentrations (hypoxia). Three human hypoxia inducible factors have been identified, HIF-1, HIF-2 and HIF-3, e...    Read more.
Read more HIF-3 alpha related blogs.