HES6 Products

Antibodies
HES6 Antibody (1D6)
HES6 Antibody (1D6)
NBP2-45971
Species: Hu
Applications: WB
Host: Mouse monoclonal
HES6 Antibody
HES6 Antibody
H00055502-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
Lysates
HES6 Overexpression Lysate (N ...
HES6 Overexpression Lysate (Native)
NBL1-11513
Applications: WB
HES6 Overexpression Lysate (D ...
HES6 Overexpression Lysate (Denatu...
H00055502-T01
Species: Hu
Applications: WB
Proteins
HES6 Recombinant Protein
HES6 Recombinant Protein
H00055502-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
HES6 RNAi
HES6 RNAi
H00055502-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

HES6 is a transcription cofactor that itself does not bind to DNA but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. It also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCFEA2/E47, allowing ASCL1 and TCFEA2 to upregulate transcription in its presence. HES6 appears to have novel functions in tumor and cancer cell lines, although these have not yet been elucidated fully.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 55502
Alternate Names
  • Hairy and enhancer of split 6
  • BHLHB41
  • HES-6
  • transcription cofactor HES-6
  • C-HAIRY1
  • bHLHc23
  • bHLHb41Class B basic helix-loop-helix protein 41
  • hairy and enhancer of split 6 (Drosophila)

PTMs for HES6

Learn more about PTMs related to HES6.

Phosphorylation
Cleavage
Acetylation

Bioinformatics Tool for HES6

Discover related pathways, diseases and genes to HES6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related HES6 Blog Posts

Check out the latest blog posts on HES6.
Using the Hif-1 Alpha Antibody in Prostate Cancer Research
The Hypoxia-inducible Factor 1 (HIF1) protein is a heterodimeric transcription factor which plays an important role in mammalian oxygen homeostasis in conditions of hypoxia, or low oxygen concentration. HIF-1 alpha antibody reagents are widely used in...    Read more.
Read more HES6 related blogs.