Hemoglobin A2 Products

Lysates
Hemoglobin A2 Overexpression ...
Hemoglobin A2 Overexpression Lysat...
NBL1-11455
Applications: WB
Proteins
Hemoglobin A2 Recombinant Pro ...
Hemoglobin A2 Recombinant Protein
NBP2-23111
Species: Hu
Applications: PAGE

Description

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta -pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) codingsequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but theydiffer significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA,which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains toconstitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemiasresult from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alphathalassemias have also been reported. (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 3040
Alternate Names
  • alpha-2 globin
  • Alpha-globin
  • alpha globin
  • hemoglobin subunit alpha
  • Hemoglobin alpha chain
  • alpha-globin
  • hemoglobin, alpha 2

PTMs for Hemoglobin A2

Learn more about PTMs related to Hemoglobin A2.

Methylation
Oxidation

Bioinformatics Tool for Hemoglobin A2

Discover related pathways, diseases and genes to Hemoglobin A2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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