H2AFJ Products

Description

Histones are nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber as they play a critical role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. The H2AFJ gene is located on chromosome 12 encodes a histone H2A.J protein that exists in two isoforms: isoform 1 is 129 amino acids long at 14 kDA while isoform 2 is 151 amino acids long at 16 kDA. The protein is divergent at the C-terminus compared to the consensus H2A histone family member. The H2AFJ gene has been researched regarding lupus, nevus, and immunodeficiency and is known to interact with various genes such as H3F3B, CENPA, ASXL2, KIAA1609, and RBBP4.

Bioinformatics

Entrez	55766 Human
Uniprot	NM_177925 Human
Product By Gene ID	55766
Alternate Names	FLJ10903 FLJ52230 H2A histone family, member J H2a/j H2AJ histone H2A.J MGC921