Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Description
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
2971 |
| Alternate Names |
- general transcription factor IIIA
- TFIIIAAP2
- transcription factor IIIA
|
