WB, Flow, IHC, NeutHost:
WB, IHC, IHC-PHost:
Growth hormone receptor encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized.
|Product By Gene ID
- serum binding protein
- growth hormone binding protein
- GH receptor
- Somatotropin receptor
- growth hormone receptor
Research Areas for Growth Hormone R
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Bioinformatics Tool for Growth Hormone R
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