Species: Mu
Applications: WB, IHC
Host: Goat Polyclonal
Species: Hu
Applications: WB, Flow, IHC, B/N, CyTOF-ready
Host: Goat Polyclonal
Species: Hu
Applications: WB, B/N
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: Bioactivity
Species: Rt
Applications: Bioactivity
Species: Hu
Applications: AC
Description
Growth hormone receptor encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
2690 |
| Alternate Names |
- GH receptor
- GHBP
- growth hormone binding protein
- growth hormone receptor
- serum binding protein
- Somatotropin receptor
|
Research Areas for Growth Hormone R
Find related products by research area and learn more about each of the different research areas below.
GPCR
![Neutralization Growth Hormone R Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Growth_Hormone_R_AF1210_Block_Neutralize_271.jpg)
