GRK1 Products

Description

The sensation of sight is the result of a cascade of events starting with the interaction of photoactivated rhodopsin with a protein called transducin. Rhodopsin kinase is a G-protein-coupled Ser/Thr kinase, also known as GRK1, which is a key element in the regulation of this cascade. Following phosphorylation by GRK1, arrestin is recruited to phospho-rhodopsin quenching its phototransductive activity by preventing further interaction with transducin. By breaking the cycle of phototransduction, GRK1 plays an important role in the restoration of the system for subsequent visual events.

Bioinformatics

Entrez	24013 Mouse 6011 Human 81760 Rat
Uniprot	NM_002929 Human NP_001155 Human NP_002920.1 Human Q15835 Human
Product By Gene ID	6011
Alternate Names	G protein-coupled receptor kinase 1rhodopsin kinase GPRK1 RHOKEC 2.7.11 RKEC 2.7.11.14

Research Areas for GRK1

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase
Signal Transduction
Vision