Species: Hu, Pm
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Bv
Applications: WB, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Bv, Ch
Applications: WB, ICC/IF, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The sensation of sight is the result of a cascade of events starting with the interaction of photoactivated rhodopsin with a protein called transducin. Rhodopsin kinase is a G-protein-coupled Ser/Thr kinase, also known as GRK1, which is a key element in the regulation of this cascade. Following phosphorylation by GRK1, arrestin is recruited to phospho-rhodopsin quenching its phototransductive activity by preventing further interaction with transducin. By breaking the cycle of phototransduction, GRK1 plays an important role in the restoration of the system for subsequent visual events.
Bioinformatics
| Entrez |
Mouse
Human
Rat
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
6011 |
| Alternate Names |
- G protein-coupled receptor kinase 1rhodopsin kinase
- GPRK1
- RHOKEC 2.7.11
- RKEC 2.7.11.14
|
