GRB 14 Products

Antibodies
GRB 14 Antibody
GRB 14 Antibody
NBP1-00863
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
GRB 14 Antibody
GRB 14 Antibody
NBP2-38230
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
GRB 14 Overexpression Lysate ...
GRB 14 Overexpression Lysate (Native)
NBL1-11325
Applications: WB
Proteins
Recombinant Human GRB 14 Prot ...
Recombinant Human GRB 14 Protein
H00002888-Q01
Species: Hu
Applications: WB, ELISA, PA
GRB 14 Recombinant Protein An ...
GRB 14 Recombinant Protein Antigen
NBP2-38230PEP
Species: Hu
Applications: AC

Description

Many growth factors function by binding receptors with intrinsic tyrosine kinase activity. Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and specific phosphotyrosine-containing receptor sequences. GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. An additional member of the GRB7 family, designated GRB14, contains a pleckstrin homology domain in its central region and a carboxy terminal SH2 domain.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 2888
Alternate Names
  • GRB14 adapter protein
  • growth factor receptor-bound protein 14

Bioinformatics Tool for GRB 14

Discover related pathways, diseases and genes to GRB 14. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.