WB, ELISA, ICC/IF, IHC, IHC-PHost:
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Hu, Mu, RtApplications:
Applications: WB, ELISA, PA, AP
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brain stem whereas the four epsilon subunits display limited distribution.
PTMs for GluR5/GRIK1
Learn more about PTMs related to GluR5/GRIK1.Phosphorylation
Bioinformatics Tool for GluR5/GRIK1
Discover related pathways, diseases and genes to GluR5/GRIK1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.