GCDH Products

Description

GCDH is encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.

Bioinformatics

Entrez	2639 Human
Uniprot	NM_000159 Human NP_000150 Human NP_000150.1 Human NP_039663 Human Q92947 Human
Product By Gene ID	2639
Alternate Names	ACAD5 EC 1.3.99 EC 1.3.99.7 GCD glutaryl-CoA dehydrogenase glutaryl-CoA dehydrogenase, mitochondrial glutaryl-Coenzyme A dehydrogenase

Diseases related to GCDH

Discover more about diseases related to GCDH.

Glutaric Aciduria, Type 1
Dystonia Disorders
Acidemia
Inborn Errors Of Metabolism
Macrocephaly
Movement Disorders
Atrophy
Brain Diseases, Metabolic
Brain Diseases, Metabolic, Inborn
Brain Injuries
Nervous System Disorder
Dyskinetic Syndrome
Nerve Degeneration
Encephalopathies
Muscle Hypotonia
Neurodegenerative Disorders
Sequelae Aspects

Pathways for GCDH

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Excretion
Transport
Pathogenesis
Succinate Transport
Host-pathogen Interaction
Chromosome Localization
Cell Proliferation
Translation
Tricarboxylic Acid Cycle
Cell Death
Localization
Myelination

Research Areas for GCDH

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Stem Cell Markers

PTMs for GCDH

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Oxidation
Carboxylation
Reduction
Decarboxylation

Bioinformatics Tool for GCDH

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