GAD65/67 Products

Antibodies
GAD65/67 Antibody
GAD65/67 Antibody
NB100-92033
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
GAD65/67 Antibody
GAD65/67 Antibody
H00002572-D01P
Species: Hu, Mu
Applications: WB, ELISA
Host: Rabbit Polyclonal

Description

GAD65/67 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

Bioinformatics

Entrez Human
Human
Uniprot Human
Human
Product By Gene ID 2571
Alternate Names
  • EC 4.1.1
  • 67kD)
  • Glutamate decarboxylase 67 kDa isoform
  • FLJ45882
  • glutamate decarboxylase 1 (brain, 67kDa)

Research Areas for GAD65/67

Find related products by research area and learn more about each of the different research areas below.

Diabetes Research
Immune System Diseases
Immunology
Neuronal Cell Markers
Neuroscience

PTMs for GAD65/67

Learn more about PTMs related to GAD65/67.

Methylation
Acetylation
Demethylation
Glycosylation
Decarboxylation

Bioinformatics Tool for GAD65/67

Discover related pathways, diseases and genes to GAD65/67. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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