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The product of the GABA Receptor Epsilon gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyricacid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptictransmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in acluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively splicedtranscript variants have been identified, but only one is thought to encode a protein. (provided by RefSeq)