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G418 Products

Inhibitors
G418 Inhibitor
G418 Inhibitor
NBP2-32805
G418 Inhibitor
G418 Inhibitor
NBP2-33053

Description

G418 is used for the selection and maintenance of eukaryotic cells expressing the neo gene1. G418 is an aminoglycoside antibiotic similar in structure to gentamycin B1, produced by Micromonospora rhodorangea. Unlike gentamycin, G418 blocks polypeptide synthesis in eukaryotic cells by binding irreversibly to 80S ribosomes and therefore disrupting their proofreading capability.