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Fragile X mental retardation syndrome-related protein 2 (FXR2) is an RNA binding protein that predominantly associates with polyribosomes. Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein, the archetype of a class of cytoplasmic mRNA-binding proteins that includes both the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.
