FPGT Products

Antibodies
FPGT Antibody
FPGT Antibody
NBP2-16527
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
FPGT Antibody
FPGT Antibody
H00008790-D01P
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
FPGT Antibody
FPGT Antibody
NBP1-31436
Species: Hu, RM
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
FPGT Overexpression Lysate (D ...
FPGT Overexpression Lysate (Denatu...
H00008790-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human FPGT Protei ...
Recombinant Human FPGT Protein
H00008790-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human FPGT Protei ...
Recombinant Human FPGT Protein
H00008790-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
FPGT RNAi
FPGT RNAi
H00008790-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 8790
Alternate Names
  • fucose-1-phosphate guanyltransferase
  • GDP-L-fucose pyrophosphorylase
  • GDP-L-fucose diphosphorylase
  • GFPPEC 2.7.7.30
  • GDP-beta-L-fucose pyrophosphorylase
  • fucose-1-phosphate guanylyltransferase

Pathways for FPGT

View related products by pathway and learn more about each of the pathways below.

Pathogenesis
Localization
Fucosylation

Bioinformatics Tool for FPGT

Discover related pathways, diseases and genes to FPGT. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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