Host: Rabbit Polyclonal
Applications: WB, ELISA, ICC/IF, IHC-P
Host: Mouse Monoclonal
WB, ELISA, IHC-PHost:
Applications: WB, ELISA, PA, AP
Applications: RNAi, RNAi SP
FOXL1 is a 337 amino acid protein encoded by the mouse gene Foxl1. FOXL1 belongs to the fork head family and contains one fork head DNA-binding domain. The HNF3/fork head family includes a large number of transcription factors that share a structurally related DNA binding domain. Fork head factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1- deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyer's patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the adenomatous polyposis coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.
|Product By Gene ID
- Forkhead-related protein FKHL11
- FKHL11forkhead-like 11
- FKH6forkhead box protein L1
- Forkhead-related transcription factor 7
- forkhead box L1
Bioinformatics Tool for FOXL1
Discover related pathways, diseases and genes to FOXL1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.