FoxD3 Products

Description

Embryonic stem cells require the forkhead transcriptional regulator FoxD3 for survival. Following gastrulation, FoxD3 generally gets downregulated, except in the neural crest. A variety of growth factors induce FoxD3 expression, including FGF8 and SNAIL, maintaining the effected cells in an undifferentiated state. Thus defects in FoxD3 induction may cause premature differentiation and/or migration-asociated birth defects.

Bioinformatics

Entrez	15221 Mouse 27022 Human
Uniprot	NP_036315 Human Q9UJU5 Human
Product By Gene ID	27022
Alternate Names	AIS1 forkhead box D3 forkhead box protein D3 HFH2 HNF3/FH transcription factor genesis

Research Areas for FoxD3

Find related products by research area and learn more about each of the different research areas below.

Embryonic Stem Cell Markers
Stem Cell Markers

Related FoxD3 Blog Posts

Check out the latest blog posts on FoxD3.

Nanog is a Master Controller of ES cell Pluripotency Nanog, a homeodomain (HD) transcription factor, plays a critical role in the maintenance of embryonic stem (ES) cell self-renewal. Transcription regulator involved in inner cell mass and ES cell proliferation and self-renewal. Imposes pluripotency on ...    Read more.

Read more FoxD3 related blogs.