Species: Hu, Mu, Ca, Pm, RM
Applications: ELISA, Flow, IHC
Host: Mouse Monoclonal
Description
PRG2 is a cytotoxin and helminthotoxin. Also induces noncytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA. In pregnancy serum, the proform exists as a disulfide-linked 2:2 heterotetramer with PAPPA, as a disulfide-linked 2:2 heterotetramer with AGT, and as a complex (probably a 2:2:2 heterohexamer) with AGT and C3dg.
Bioinformatics
| Alternate Names |
- BMPG
- Bone marrow proteoglycan
- EMBP
- Eosinophil granule major basic protein
- Eosinophil major basic protein
- MBP
- MGC14537
- MPG
- Natural killer cell activator
- Pregnancy associated major basic protein
- PRG 2
- Proteoglycan 2 bone marrow
- Proteoglycan 2 preproprotein
- Proteoglycan 2
- Proteoglycan2
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