ELAC2 Products

Antibodies
ELAC2 Antibody
ELAC2 Antibody
NBP1-84620
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
ELAC2 Antibody - BSA Free
ELAC2 Antibody - BSA Free
NBP3-04612
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
ELAC2 Antibody
ELAC2 Antibody
NBP3-12934
Species: Hu, Pm
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Lysates
ELAC2 Overexpression Lysate
ELAC2 Overexpression Lysate
NBL1-10223
Species: Hu
Applications: WB
Proteins
Recombinant Human ELAC2 GST ( ...
Recombinant Human ELAC2 GST (N-Ter...
H00060528-Q01
Species: Hu
Applications: WB, ELISA, MA, AP
ELAC2 Recombinant Protein Ant ...
ELAC2 Recombinant Protein Antigen
NBP1-84620PEP
Species: Hu
Applications: AC

Description

The protein encoded by the ELAC2 gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity,which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activatedSmad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expressioncan suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased riskof prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. (providedby RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Alternate Names
  • EC 3.1.26.11
  • elaC homolog 2 (E. coli)
  • ElaC homolog protein 2
  • ELC2
  • FLJ10530
  • FLJ36693
  • FLJ42848
  • Heredity prostate cancer protein 2
  • HPC2elaC (E. coli) homolog 2
  • putative prostate cancer susceptibility protein HPC2/ELAC2
  • Ribonuclease Z 2
  • RNase Z 2
  • tRNA 3 endonuclease 2
  • tRNase Z (long form)
  • tRNase Z 2
  • zinc phosphodiesterase ELAC protein 2