ECEL1 Products

Description

ECEL1 encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. This gene is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. This gene has multiple pseudogenes. [provided by RefSeq]

Bioinformatics

Entrez	9427 Human
Uniprot	AAH50453.2 Human NM_004826 Human O95672 Human
Product By Gene ID	9427
Alternate Names	damage induced neuronal endopeptidase DINE EC 3.4.24 EC 3.4.24.- EC 3.4.24.11 ECEX endothelin converting enzyme-like 1 endothelin-converting enzyme-like 1 Xce protein XCEX converting enzyme

Research Areas for ECEL1

Find related products by research area and learn more about each of the different research areas below.

Neuroscience