E2F5 Products

Antibodies
E2F5 Antibody
E2F5 Antibody
NBP2-56500
Species: Hu, Mu
Applications: ICC/IF
Host: Rabbit Polyclonal
Lysates
E2F5 Overexpression Lysate (N ...
E2F5 Overexpression Lysate (Native)
NBP2-08161
Applications: WB
Proteins
E2F5 Recombinant Protein Anti ...
E2F5 Recombinant Protein Antigen
NBP2-56500PEP
Species: Hu
Applications: B/N, Ctrl
RNAi
E2F5 RNAi
E2F5 RNAi
H00001875-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The protein encoded by the E2F5 gene is a member of the E2F family of transcription factors. The E2F family plays a crucialrole in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transformingproteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that arepresent in most members of the family. These domains include a DNA binding domain, a dimerization domain whichdetermines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domainenriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within thetransactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of humantissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumorsuppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encodingdifferent isoforms. (provided by RefSeq)

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 1875
Alternate Names
  • transcription factor E2F5
  • E2F-5
  • E2F transcription factor 5, p130-binding

Research Areas for E2F5

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

Bioinformatics Tool for E2F5

Discover related pathways, diseases and genes to E2F5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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