DUSP4 Products

Antibodies
DUSP4 Antibody
DUSP4 Antibody
NBP1-19592
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
DUSP4 Antibody (1D12)
DUSP4 Antibody (1D12)
H00001846-M08
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
DUSP4 Antibody
DUSP4 Antibody
NBP1-68021
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
DUSP4 Overexpression Lysate ( ...
DUSP4 Overexpression Lysate (Native)
NBL1-10054
Applications: WB
DUSP4 Overexpression Lysate ( ...
DUSP4 Overexpression Lysate (Native)
NBL1-10055
Applications: WB
DUSP4 Overexpression Lysate ( ...
DUSP4 Overexpression Lysate (Denat...
H00001846-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human DUSP4 Prote ...
Recombinant Human DUSP4 Protein
H00001846-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
DUSP4 RNAi
DUSP4 RNAi
H00001846-R02
Species: Hu
Applications: RNAi, RNAi SP
DUSP4 RNAi
DUSP4 RNAi
H00001846-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP- 4. Human MKP-2 maps to chromosome 8p12-p11 and encodes a 394 amino acid, 43 kDa protein that specifically inactivates ERK1, ERK2 and JNK.

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 1846
Alternate Names
  • VH2
  • Mitogen-activated protein kinase phosphatase 2
  • EC 3.1.3.48
  • Dual specificity protein phosphatase hVH2
  • EC 3.1.3.16
  • TYP
  • MKP2VH1 homologous phosphatase 2
  • HVH2serine/threonine specific protein phosphatase
  • MKP-2dual specificity protein phosphatase 4
  • MAP kinase phosphatase 2
  • dual specificity phosphatase 4

Research Areas for DUSP4

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

Bioinformatics Tool for DUSP4

Discover related pathways, diseases and genes to DUSP4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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