DOK6 Products

Antibodies
DOK6 Antibody
DOK6 Antibody
NBP2-32609
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
DOK6 Antibody
DOK6 Antibody
NBP2-16211
Species: Mu
Applications: WB
Host: Rabbit Polyclonal
Lysates
DOK6 Overexpression Lysate (N ...
DOK6 Overexpression Lysate (Native)
NBL1-09981
Applications: WB
Proteins
DOK6 Recombinant Protein
DOK6 Recombinant Protein
H00220164-P01
Species: Hu
Applications: WB, ELISA, PA
DOK6 Recombinant Protein Anti ...
DOK6 Recombinant Protein Antigen
NBP2-32609PEP
Species: Hu
Applications: AC

Description

The downstream of kinase family (Dok1-6) are members of a class of "docking" proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. The gene encoding human Dok-5 maps to chromosomal location 20q13.2. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 220164
Alternate Names
  • docking protein 5-like
  • DOK5L
  • Downstream of tyrosine kinase 6
  • MGC20785
  • HsT3226
  • docking protein 6

Pathways for DOK6

View related products by pathway and learn more about each of the pathways below.

System Development
Nervous System Development
Chromosome Breakage
Glomerular Filtration
Kidney Development

PTMs for DOK6

Learn more about PTMs related to DOK6.

Phosphorylation

Bioinformatics Tool for DOK6

Discover related pathways, diseases and genes to DOK6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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