WB, IHC, IHC-PHost:
Host: Mouse Polyclonal
Host: Rabbit Polyclonal
Applications: Bioactivity, Enzyme Activity
DNASE1, also known as Deoxyribonuclease 1, is an endonuclease found in the zymogen granules of the nuclear envelope. Responsible for DNA fragmentation and cell death during apoptosis, DNASE1 binds to G-actin and blocks actin polymerization. Mutations in DNASE1 cause systemic lupus erythematosus (SLE), an autoimmune disease causing inflammation and tissue damage. DNASE1 is also known to treat symptoms of cystic fibrosis.
|Product By Gene ID
- DNase I
- human urine deoxyribonuclease I
- EC 184.108.40.206
- DNase I, lysosomal
- Dornase alfa
- deoxyribonuclease IFLJ38093
Bioinformatics Tool for DNASE1
Discover related pathways, diseases and genes to DNASE1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.