DNASE1 Products

Antibodies
DNASE1 Antibody
DNASE1 Antibody
NBP1-84999
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
DNASE1 Antibody
DNASE1 Antibody
NBP1-59404
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
DNASE1 Antibody
DNASE1 Antibody
H00001773-B01P
Species: Hu
Applications: WB
Host: Mouse Polyclonal
Lysates
DNASE1 Overexpression Lysate ...
DNASE1 Overexpression Lysate (Dena...
H00001773-T01
Species: Hu
Applications: WB
DNASE1 Overexpression Lysate ...
DNASE1 Overexpression Lysate (Native)
NBL1-09959
Applications: WB
Proteins
DNASE1 Recombinant Protein An ...
DNASE1 Recombinant Protein Antigen
NBP1-84999PEP
Species: Hu
Applications: AC
DNASE1 Native Protein
DNASE1 Native Protein
P5224
Species: Bv

Description

DNASE1, also known as Deoxyribonuclease 1, is an endonuclease found in the zymogen granules of the nuclear envelope. Responsible for DNA fragmentation and cell death during apoptosis, DNASE1 binds to G-actin and blocks actin polymerization. Mutations in DNASE1 cause systemic lupus erythematosus (SLE), an autoimmune disease causing inflammation and tissue damage. DNASE1 is also known to treat symptoms of cystic fibrosis.

Bioinformatics

Entrez Human
Bovine
Uniprot Human
Human
Human
Human
Product By Gene ID 1773
Alternate Names
  • DNase I
  • DKFZp686H0155
  • human urine deoxyribonuclease I
  • EC 3.1.21.1
  • DNase I, lysosomal
  • Dornase alfa
  • deoxyribonuclease-1
  • DRNI
  • DNL1FLJ44902
  • deoxyribonuclease IFLJ38093

Research Areas for DNASE1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
DNA Repair
DNA replication, Transcription, Translation and Splicing

PTMs for DNASE1

Learn more about PTMs related to DNASE1.

Cleavage
Glycosylation

Bioinformatics Tool for DNASE1

Discover related pathways, diseases and genes to DNASE1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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