DEDD Products

Description

This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.

Bioinformatics

Entrez	9191 Human
Uniprot	NP_127491 Human
Product By Gene ID	9191
Alternate Names	CASP8IP1 death effector domain containing death effector domain-containing protein Death effector domain-containing testicular molecule death effector domain-containing DEDD1 DEDPRO1 DEFTKE05 FLDED1 FLDED-1

Research Areas for DEDD

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Apoptosis