DDX23 Products

Description

DDX23 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.

Bioinformatics

Entrez	74351 Mouse 9416 Human
Uniprot	NM_004818 Human NP_004809.2 Human Q9BUQ8 Human
Product By Gene ID	9416
Alternate Names	100 kDa U5 snRNP-specific protein DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 DEAD box protein 23 EC 3.6.1 EC 3.6.4.13 MGC8416 probable ATP-dependent RNA helicase DDX23 PRP28 homolog PRP28 homolog, yeast PRP28 prp28 PRP28p homolog PRPF28 U5 snRNP 100 kD protein U5-100K U5-100KD U5-100kD

Research Areas for DDX23

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Cell Cycle and Replication