Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, Mycoplasma
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
DDX18 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX18 has been observed to be a target of myc-max heterodimers. Alternate names for DDX18 include ATP-dependent RNA helicase DDX18, DEAD box protein 18, myc-regulated DEAD box protein, and MrDb.
Bioinformatics
| Entrez |
Human |
| Uniprot |
Human |
| Product By Gene ID |
8886 |
| Alternate Names |
- DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
- DEAD box protein 18
- DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 18 (Myc-regulated)
- EC 3.6.1
- EC 3.6.4.13
- FLJ33908
- MrDbATP-dependent RNA helicase DDX18
- Myc-regulated DEAD box protein
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