DAZAP1 Products

Description

In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.

Bioinformatics

Entrez	26528 Human
Uniprot	NP_061832 Human
Product By Gene ID	26528
Alternate Names	DAZ associated protein 1 DAZ-associated protein 1 deleted in azoospermia associated protein 1 Deleted in azoospermia-associated protein 1 MGC19907

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