Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu
Applications: WB, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Description
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. Keratin 17 is expressed in suprabasal keratinocytes of wounded epidermis. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. LdS 23 is useful for studies of epithelial cells and tumour origin.
Bioinformatics
| Product By Gene ID |
3855 |
| Alternate Names |
- CK7
- CK-7
- cytokeratin 7
- Cytokeratin-7
- cytokeratin-7
- K2C7
- K7keratin, 55K type II cytoskeletal
- keratin 7
- keratin, type II cytoskeletal 7
- Keratin-7
- keratin-7
- MGC129731
- MGC3625
- Sarcolectin
- sarcolectin
- SCLkeratin, simple epithelial type I, K7
- type II mesothelial keratin K7
- Type-II keratin Kb7
|
Research Areas for Cytokeratin 7/13/17/18
Find related products by research area and learn more about each of the different research areas below.
Cytoskeleton Markers