Applications: WB, IHC, IHC-Fr, IP, IF
Host: Mouse Monoclonal
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. Keratin 17 is expressed in suprabasal keratinocytes of wounded epidermis. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. LdS 23 is useful for studies of epithelial cells and tumour origin.
|Product By Gene ID
- cytokeratin 7
- type II mesothelial keratin K7
- Type-II keratin Kb7
- keratin, type II cytoskeletal 7
- SCLkeratin, simple epithelial type I, K7
- K7keratin, 55K type II cytoskeletal
- keratin 7
Research Areas for Cytokeratin 7/13/17/18
Find related products by research area and learn more about each of the different research areas below.Cytoskeleton Markers
Bioinformatics Tool for Cytokeratin 7/13/17/18
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