Cytokeratin 4 Products

Antibodies
Cytokeratin 4 Antibody
Cytokeratin 4 Antibody
NBP1-33412
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Cytokeratin 4 Antibody (5H5)
Cytokeratin 4 Antibody (5H5)
H00003851-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Cytokeratin 4 Antibody
Cytokeratin 4 Antibody
NBP2-33984
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
Cytokeratin 4 Antibody Pair
Cytokeratin 4 Antibody Pair
H00003851-AP11
Species: Hu
Applications: S-ELISA
Lysates
Cytokeratin 4 Overexpression ...
Cytokeratin 4 Overexpression Lysat...
H00003851-T01
Species: Hu
Applications: WB
Cytokeratin 4 Overexpression ...
Cytokeratin 4 Overexpression Lysat...
NBP2-10820
Applications: WB
Proteins
Cytokeratin 4 Partial Recombi ...
Cytokeratin 4 Partial Recombinant ...
H00003851-Q01
Species: Hu
Applications: WB, ELISA, PA
Cytokeratin 4 Recombinant Pro ...
Cytokeratin 4 Recombinant Protein
H00003851-P01
Species: Hu
Applications: WB, ELISA, PA
Cytokeratin 4 Recombinant Pro ...
Cytokeratin 4 Recombinant Protein ...
NBP2-33984PEP
Species: Hu
Applications: AC
RNAi
Cytokeratin 4 RNAi
Cytokeratin 4 RNAi
H00003851-R01
Species: Hu

Description

Keratins are a family of structurally related proteins that form the intermediate filament cytoskeleton in epithelial cells. White sponge nevus (WSN) is a benign autosomal dominant disorder which affects non-cornifying stratified squamous epithelial. Keratins are expressed in pairs by epithelial cells in a tissue and cell specific manner. The major differentiation specific keratins of the buccal mucosa, nasal, esophageal and anogenital epithelia are CK-4 and CK-13. The tissue distribution and nature of the lesions in patients affected by WSN suggested that mutations in CK-4 and/or CK-13 might be responsible for this disorder (1). K4 and K13 form heterodimers in normal epithelial cells. In humans, K4 is present in all layers of the epidermis at 10 weeks and gradually disappears, starting from the basal layers at 15 weeks and becoming totally absent at around 20 weeks. This period corresponds to the early fetal period when melanoblasts derived from the neural crest migrate through the dermis into the basal layer of the epidermis (2)

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 3851
Alternate Names
  • Keratin-4
  • CK-4
  • Cytokeratin-4
  • Type-II keratin Kb4
  • keratin, type II cytoskeletal 4
  • CK4
  • CYK4cytokeratin-4
  • K4cytokeratin 4
  • FLJ31692
  • keratin 4

Research Areas for Cytokeratin 4

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cytoskeleton Markers

PTMs for Cytokeratin 4

Learn more about PTMs related to Cytokeratin 4.

Phosphorylation

Bioinformatics Tool for Cytokeratin 4

Discover related pathways, diseases and genes to Cytokeratin 4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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