Cytochrome P450 3A7 Products

Antibodies
Cytochrome P450 3A7 Antibody ...
Cytochrome P450 3A7 Antibody (F19 ...
NB100-74402
Species: Hu, Bv
Applications: WB, ELISA, Flow, IHC, IHC-P
Host: Mouse Monoclonal

Description

The Cytochrome P450 (P450) family of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as NADPH and P450 reductase. There are over 200 cDNA®s which encode P450 protein. Epoxygenases are those P450 proteins which metabolize AA to epoxyeicosatrienoic acid (EETs) and w-hydroxylases are those P450 proteins which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). 20-HETE is converted from AA by the 4A family of P450 proteins which includes at least 8 different, though closely related isoforms. 4A1, 4A2, & 4A3 have been cloned from liver, kidney and testis and have been detected in renal, hepatic & brain microvessels.

Bioinformatics

Alternate Names
  • Aryl hydrocarbon hydroxylase
  • subfamily IIIA
  • subfamily A
  • polypeptide 7
  • family 3
  • Xenobiotic monooxygenase
  • P450 HFLA
  • Microsomal monooxygenase
  • Flavoprotein linked monooxygenase
  • Cytochrome P450 3A7
  • cytochrome P450
  • CYPIIIA7
  • CP37