CRMP2 Products

Antibodies
CRMP2 Antibody
CRMP2 Antibody
NBP1-85448
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
CRMP2 Antibody
CRMP2 Antibody
NBP1-31762
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
CRMP2 Antibody (33CT11.40.3)
CRMP2 Antibody (33CT11.40.3)
NBP1-50580
Species: Hu, Mu, Rt, Bv, Ch
Applications: WB, IHC-P
Host: Mouse Monoclonal
Proteins
Recombinant Human CRMP2 Prote ...
Recombinant Human CRMP2 Protein
H00001808-P01
Species: Hu
Applications: WB, ELISA, PA, PAGE
Recombinant Human CRMP2 Prote ...
Recombinant Human CRMP2 Protein
H00001808-Q01
Species: Hu
Applications: WB, ELISA, PA
CRMP2 Recombinant Protein Ant ...
CRMP2 Recombinant Protein Antigen
NBP1-85448PEP
Species: Hu
Applications: AC

Description

Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance. CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification. The CRMPs appear to play a complex role in axon growth as well as microtubule dynamics and axon induction. CRMPs localize to the lamellipodia and filopodia of axonal growth cones, suggesting a role in axon guidance. Moreover, CRMP2 is upregulated after axotomy, and appears to increase the formation of axon-type processes from hippocampal neurons. CRMP2 has been reported to bind tubulin dimers directly and modulate microtubule assembly. CRMPs have also been implicated in the pathogenesis of a paraneoplastic neurologic syndrome. Interaction studies have implicated phospholipase D2 (PLD2), the cytosolic tyrosine kinase Fes, and intersectin in CRMP function. Hyperphosphorylation of CRMP2 is an early event in the progression of Alzheimer's disease.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 1808
Alternate Names
  • ULIP2
  • Unc-33-like phosphoprotein 2
  • dihydropyrimidinase-related protein 2
  • Collapsin response mediator protein 2
  • dihydropyrimidinase-like 2 long form
  • DHPRP2
  • DRP2collapsin response mediator protein hCRMP-2
  • DRP-2ULIP-2
  • CRMP2N2A3
  • CRMP-2
  • dihydropyrimidinase-like 2

Research Areas for CRMP2

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Phospho-Specific

PTMs for CRMP2

Learn more about PTMs related to CRMP2.

Phosphorylation
Methylation
Glycosylation
Cleavage

Bioinformatics Tool for CRMP2

Discover related pathways, diseases and genes to CRMP2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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