Species: Hu, Rt
Applications: WB, Simple Western, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
PPP1R14A (Protein phosphatase 1 regulatory subunit 14A) is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. Myosin phosphatase can reverse MYL (myosin light chain) phosphorylation to induce a state of relaxation. However, during agonist-induced contraction at constant Ca2+ concurrent inhibition of myosin phosphatase leads to increases in MYL phosphorylation and tension. These calcium-independent increases in myosin phosphorylation and tension are termed calcium sensitization.
Bioinformatics
| Uniprot |
Human |
| Product By Gene ID |
94274 |
| Alternate Names |
- 17 kDa PKC-potentiated inhibitory protein of PP1
- CPI-1717-kDa PKC-potentiated inhibitory protein of PP1
- CPI1717-KDa protein
- PKC-potentiated inhibitory protein of PP1
- PPP1INL
- Protein kinase C-potentiated inhibitor protein of 17 kDa
- protein phosphatase 1 regulatory subunit 14A
- protein phosphatase 1, regulatory (inhibitor) subunit 14A
|
Research Areas for CPI17 alpha
Find related products by research area and learn more about each of the different research areas below.
Protein Phosphatase