COX7A2L Products

Description

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.

Bioinformatics

Entrez	9167 Human
Uniprot	AAH05251 Human
Product By Gene ID	9167
Alternate Names	COX7ARcytochrome c oxidase subunit VII-related protein COX7a-related protein COX7RPmitochondrial cytochrome c oxidase subunit VIIa polypeptide 2 like Cytochrome c oxidase subunit VIIa-related protein estrogen receptor binding CpG island SIG81

Research Areas for COX7A2L

Find related products by research area and learn more about each of the different research areas below.

Cancer
Neurodegeneration
Neuroscience
Signal Transduction