Collagen I/II/III Products

Description

Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.

Bioinformatics

Entrez	1277 Human
Uniprot	P02452 Human
Product By Gene ID	1277
Alternate Names	Alpha-1 type I collagen collagen alpha 1 chain type I collagen alpha-1(I) chain collagen of skin, tendon and bone, alpha-1 chain collagen, type I, alpha 1 OI4 pro-alpha-1 collagen type 1

Research Areas for Collagen I/II/III

Find related products by research area and learn more about each of the different research areas below.

Cytoskeleton Markers
Extracellular Matrix