Species: Hu
Applications: WB, Simple Western, ICC/IF
Host: Goat Polyclonal
Species: Hu, Mu, Rt, Po, Bv, RM
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rat Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. [provided by RefSeq]
Bioinformatics
| Product By Gene ID |
1154 |
| Alternate Names |
- CIS-1
- CIS-1cytokine-inducible SH2-containing protein
- CIScytokine-inducible inhibitor of signaling type 1B
- CISH
- cytokine inducible SH2-containing protein
- G18Protein G18
- SOCS
- Suppressor of cytokine signaling
|
Research Areas for CISH/CIS-1
Find related products by research area and learn more about each of the different research areas below.
Signal Transduction
![Western Blot CISH/CIS-1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/CIS-1_AF3194_Western_Blot_5249.jpg)
![Western Blot CISH/CIS-1 Antibody (989616) [Unconjugated]](http://images.novusbio.com/fullsize2/CIS1_MAB3194_Western_Blot_22247.jpg)
![Immunocytochemistry CISH/CIS-1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/af3194_human-cis-1-affinity-purified-polyclonal-ab-immunocytochemistry-309202194844.jpg)
![Simple Western CISH/CIS-1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/af3194_human-cis-1-affinity-purified-polyclonal-ab-simple-western-1342022124434.jpg)
