Species: Hu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
Species: Hu
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Mu, Rt
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: Rt
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
CENPB product is a highly conserved protein associated with the centromere. It is a DNA-binding protein containing a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
1059 |
| Alternate Names |
- CENP-B
- centromere autoantigen B
- centromere protein B (80kD)
- Centromere protein B
- centromere protein B, 80kDa
- major centromere autoantigen B
|
