Cdk9 Products

Cdk9 Antibody (SD204-07)
Cdk9 Antibody (SD204-07)
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Monoclonal
Cdk9 Antibody (2D7)
Cdk9 Antibody (2D7)
Species: Hu, Dr
Applications: WB, ELISA, ICC/IF, IP
Host: Mouse Monoclonal
Cdk9 Antibody
Cdk9 Antibody
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Human Cdk9 ELISA Kit (Colorim ...
Human Cdk9 ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
Mouse Cdk9 ELISA Kit (Colorim ...
Mouse Cdk9 ELISA Kit (Colorimetric)
Species: Mu
Applications: ELISA
Rat Cdk9 ELISA Kit (Colorimet ...
Rat Cdk9 ELISA Kit (Colorimetric)
Species: Rt
Applications: ELISA
Cdk9 Recombinant Protein Anti ...
Cdk9 Recombinant Protein Antigen
Species: Hu
Applications: AC
Recombinant Human Cdk9 Protei ...
Recombinant Human Cdk9 Protein
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human Cdk9 Protei ...
Recombinant Human Cdk9 Protein
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP


CDK9 (PITALRE) (also known as cyclin-dependent kinase 9, Serine/threonine-protein kinase PITALRE, C-2K and Cell division cycle 2-like protein kinase 4) is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. CDK9 (PITALRE) interacts with a conserved domain in the TRAF-C region of the tumor necrosis factor signal transducer TRAF2. This kinase also was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. Tat stimulates human HIV-1 viral transcription elongation. This suggests that cyclin T1/cdk9(PITALRE) is one of the HIV-1 required host cellular cofactors generated during T cell activation. Cyclin T1/cdk9(PITALRE) is shown to interact with Tat to restore Tat activation in HeLa nuclear extracts depleted of P-TEFb. The cdk9(PITALRE) activity and cyclin T1 are essential for activation of transcription when tethered to the heterologous Rev response element RNA via the regulator of expression of virion Rev. CDK9 (PITALRE) is a ubiquitously expressed nuclear protein.


Entrez Human
Uniprot Human
Product By Gene ID 1025
Alternate Names
  • EC 2.7.11
  • Serine/threonine-protein kinase PITALRE
  • EC
  • Cell division protein kinase 9
  • EC
  • Cell division cycle 2-like protein kinase 4
  • C-2K
  • TAK
  • serine/threonine protein kinase PITALRE
  • CDC2-related kinase
  • C-2k
  • CDC2L4CTK1
  • cyclin-dependent kinase 9 (CDC2-related kinase)
  • cyclin-dependent kinase 9

Research Areas for Cdk9

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Signal Transduction
Virology, Bacteria and Parasites

Bioinformatics Tool for Cdk9

Discover related pathways, diseases and genes to Cdk9. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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